MovDisordV3, Main, Exploration, bibRecord, 002F78

Bright light therapy in Parkinson's disease: A pilot study

Identifieur interne : 002F78 ( Main/Exploration ); précédent : 002F77; suivant : 002F79

Bright light therapy in Parkinson's disease: A pilot study

Auteurs : Sebastian Paus [Allemagne] ; Tanja Schmitz-Hübsch [Allemagne] ; Ullrich Wüllner [Allemagne] ; Antje Vogel [Allemagne] ; Thomas Klockgether [Allemagne] ; Michael Abele [Allemagne]

Source :

Movement Disorders [ 0885-3185 ] ; 2007-07-30.

RBID : ISTEX:F3E617767F9299F68BA360DDFD2E4C37C5A305E3

Descripteurs français

Pascal (Inist)
- Etat dépressif, Lumière, Mélatonine, Parkinson maladie, Système nerveux pathologie, Traitement, Tremblement.

English descriptors

KwdEn :
- Aged, Depression, Depression (etiology), Depression (therapy), Double-Blind Method, Female, Humans, Light, Male, Melatonin, Middle Aged, Nervous system diseases, Parkinson Disease (complications), Parkinson Disease (therapy), Parkinson disease, Parkinson's Disease, Phototherapy (methods), Pilot Projects, Retrospective Studies, Severity of Illness Index, Sleep Disorders (etiology), Sleep Disorders (therapy), Treatment, Treatment Outcome, Tremor, bright light therapy, depression, melatonin, tremor.
MESH :
- complications : Parkinson Disease.
- etiology : Depression, Sleep Disorders.
- methods : Phototherapy.
- therapy : Depression, Parkinson Disease, Sleep Disorders.
- Aged, Double-Blind Method, Female, Humans, Male, Middle Aged, Pilot Projects, Retrospective Studies, Severity of Illness Index, Treatment Outcome.

Abstract

Several observations suggest a beneficial effect of melatonin antagonism for Parkinson's disease (PD). Although bright light therapy (BLT) suppresses melatonin release and is an established treatment for depression and sleep disturbances, it has not been evaluated in PD. We examined effects of BLT on motor symptoms, depression, and sleep in PD in a randomized placebo‐controlled double‐blind study in 36 PD patients, using Parkinson's Disease Rating Scale (UPDRS) I–IV, Beck's Depression Inventory, and Epworth Sleepiness Scale. All patients received BLT for 15 days in the morning, 30 min daily. Illuminance was 7.500 lux in the active treatment group and 950 lux in the placebo group. Although group differences were small, BLT led to significant improvement of tremor, UPDRS I, II, and IV, and depression in the active treatment group but not in the placebo group. It was very well tolerated. Follow up studies in more advanced patient populations employing longer treatment durations are warranted. © 2007 Movement Disorder Society

Url:

https://api.istex.fr/document/F3E617767F9299F68BA360DDFD2E4C37C5A305E3/fulltext/pdf

DOI: 10.1002/mds.21542

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">Several observations suggest a beneficial effect of melatonin antagonism for Parkinson's disease (PD). Although bright light therapy (BLT) suppresses melatonin release and is an established treatment for depression and sleep disturbances, it has not been evaluated in PD. We examined effects of BLT on motor symptoms, depression, and sleep in PD in a randomized placebo‐controlled double‐blind study in 36 PD patients, using Parkinson's Disease Rating Scale (UPDRS) I–IV, Beck's Depression Inventory, and Epworth Sleepiness Scale. All patients received BLT for 15 days in the morning, 30 min daily. Illuminance was 7.500 lux in the active treatment group and 950 lux in the placebo group. Although group differences were small, BLT led to significant improvement of tremor, UPDRS I, II, and IV, and depression in the active treatment group but not in the placebo group. It was very well tolerated. Follow up studies in more advanced patient populations employing longer treatment durations are warranted. © 2007 Movement Disorder Society</div>
</front>
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Movement Disorders (revue)

Bright light therapy in Parkinson's disease: A pilot study

Bright light therapy in Parkinson's disease: A pilot study

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
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